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Why some people get worse colds than others

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The organisms that live inside your nose could determine the type and severity of the cold symptoms you develop, a new study has found.

Researchers say that people with more bacteria in their noses that causes lower respiratory tract infections, food poisoning and boils are also more likely to cough and sneeze when they get the common cold. 

Past evidence has shown that the bacteria found in the gut can influence innate immune responses.

The team from the University of Virginia School of Medicine says their findings shed fresh light on the elusive common cold and could pave the way to individualized treatments for the virus.

For the study, the team looked at the nasal microbiome of 152 participants both before and after injecting them with rhinovirus type 39, a common cold virus.

This was to confirm the collection of bacteria wouldn’t be greatly altered after they got sick.

To analyze the microbiome, researchers took nasal swabs and stool samples and evaluated them – and symptoms – over the next five days. 

The team found that the nasal bacteria could fall into one of six patterns – and symptom severity depended on which the pattern the volunteer had.

The pattern was also associated with viral load, or the amount rhinovirus in the body. 

Findings showed that cold sufferers whose noses had a great deal of Staphylococcus bacteria had more severe nasal symptoms than those with less staph.

This bacteria can cause boils, food poisoning, impetigo and toxic shock syndrome.  

In addition, those with more Moraxella – which causes lowers respiratory tract infections – also had worse symptoms and a greater viral load.

These differences in symptoms were despite the fact that the participants’ colds were caused by the same viral strain.

Researchers admitted they were surprised by their discovery.

‘The first surprise was that you can kind of identify these different buckets that people kind of fit into,’ said Dr Ronald Turner, a professor of pediatrics at the University of Virginia School of Medicine.

‘And then the fact that the buckets seem to have some impact on how you respond to the virus and how sick you get was also interesting,’  

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‘So the background microbiome, the background bacterial pattern in your nose, had influences on the way that you reacted to the virus and how sick you got.’

In addition, the team wanted to see if giving the participants probiotics, or good bacteria, would alleviate their cold symptoms or change the makeup of their nasal microbiomes.

All the participants were given a liquid probiotic to drink, but it did not affect the bacteria in the participants’ noses or in their stomachs.

Dr Turner said it’s possible that a nasal spray probiotic might be more effective, but that would require further research.  

‘It’s not going to be so simple, I don’t think, as saying: “OK, what happens if you give a probiotic?”‘ he said. 

‘One of the things that would be interesting to ask, and this would be a completely different study, is, what happens if you give antibiotics? 

‘Can you change the nasal flora by giving antibiotic? And is that a good thing or is that a bad thing? Those are all unknowns.’ 

He added that more research is also needed to determine the exact link between the nasal microbiome and the severity of cold symptoms.

‘What we’re reporting is an association, so it’s entirely possible that the fact that you have staph in your nose and you have more symptoms is not directly related,’ Dr Turner said.

‘It may well be that there’s some underlying host characteristic that makes you likely to have staph in your nose and also makes you more likely to become ill.’  

This means that a person’s genes could be responsible for the makeup of nasal bacteria and symptom severity.

Dr Turner said there could also be environmental elements that are at play. 

‘Whether you’re exposed to pollution or whether you’re allergic or whether any number of things might impact it, I don’t know,’ he said. 

‘But I suspect there is some interaction among the host and the environment and the pathogen that determines what you end up with.’   

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Public officers above 58 years and with pre-existing conditions told to work from home: The Standard

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Head of Public Service Joseph Kinyua. [File, Standard]
In a document from Head of Public Service, Joseph Kinyua new measure have been outlined to curb the bulging spread of covid-19. Public officers with underlying health conditions and those who are over 58 years -a group that experts have classified as most vulnerable to the virus will be required to execute their duties from home.

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However, the new rule excluded personnel in the security sector and other critical and essential services.
“All State and public officers with pre-existing medical conditions and/or aged 58 years and above serving in CSG5 (job group ‘S’) and below or their equivalents should forthwith work from home,” read the document,” read the document.
To ensure that those working from home deliver, the Public Service directs that there be clear assignments and targets tasked for the period designated and a clear reporting line to monitor and review work done.
SEE ALSO: Thinking inside the cardboard box for post-lockdown work stations
Others measures outlined in the document include the provision of personal protective equipment to staff, provision of sanitizers and access to washing facilities fitted with soap and water, temperature checks for all staff and clients entering public offices regular fumigation of office premises and vehicles and minimizing of visitors except by prior appointments.
Officers who contract the virus and come back to work after quarantine or isolation period will be required to follow specific directives such as obtaining clearance from the isolation facility certified by the designated persons indicating that the public officer is free and safe from Covid-19. The officer will also be required to stay away from duty station for a period of seven days after the date of medical certification.
“The period a public officer spends in quarantine or isolation due to Covid-19, shall be treated as sick leave and shall be subject to the Provisions of the Human Resource Policy and procedures Manual for the Public Service(May,2016),” read the document.
The service has also made discrimination and stigmatization an offence and has guaranteed those affected with the virus to receive adequate access to mental health and psychosocial supported offered by the government.
The new directives targeting the Public Services come at a time when Kenyans have increasingly shown lack of strict observance of the issued guidelines even as the number of positive Covid-19 cases skyrocket to 13,771 and leaving 238 dead as of today.
SEE ALSO: Working from home could be blessing in disguise for persons with disabilities
Principal Secretaries/ Accounting Officers will be personally responsible for effective enforcement and compliance of the current guidelines and any future directives issued to mitigate the spread of Covid-19.

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Uhuru convenes summit to review rising Covid-19 cases: The Standard

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President Uhuru Kenyatta (pictured) will on Friday, July 24, meet governors following the ballooning Covid-19 infections in recent days.
The session will among other things review the efficacy of the containment measures in place and review the impact of the phased easing of the restrictions, State House said in a statement.
This story is being updated.
SEE ALSO: Sakaja resigns from Covid-19 Senate committee, in court tomorrow

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Drastic life changes affecting mental health

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Kenya has been ranked 6th among African countries with the highest cases of depression, this has triggered anxiety by the World Health Organization (WHO), with 1.9 million people suffering from a form of mental conditions such as depression, substance abuse.

KBC Radio_KICD Timetable

Globally, one in four people is affected by mental or neurological disorders at some point in their lives, this is according to the WHO.

Currently, around 450 million people suffer from such conditions, placing mental disorders among the leading causes of ill-health and disability worldwide.

The pandemic has also been known to cause significant distress, mostly affecting the state of one’s mental well-being.

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With the spread of the COVID-19 pandemic attributed to the novel Coronavirus disease, millions have been affected globally with over 14 million infections and half a million deaths as to date. This has brought about uncertainty coupled with difficult situations, including job loss and the risk of contracting the deadly virus.

In Kenya the first Coronavirus case was reported in Nairobi by the Ministry of Health on the 12th March 2020.  It was not until the government put in place precautionary measures including a curfew and lockdown (the latter having being lifted) due to an increase in the number of infections that people began feeling its effect both economically and socially.

A study by Dr. Habil Otanga,  a Lecturer at the University of Nairobi, Department of Psychology says  that such measures can in turn lead to surge in mental related illnesses including depression, feelings of confusion, anger and fear, and even substance abuse. It also brings with it a sense of boredom, loneliness, anger, isolation and frustration. In the post-quarantine/isolation period, loss of employment due to the depressed economy and the stigma around the disease are also likely to lead to mental health problems.

The Kenya National Bureau of Statistics (KNBS) states that at least 300,000 Kenyans have lost their jobs due to the Coronavirus pandemic between the period of January and March this year.

KNBC noted that the number of employed Kenyans plunged to 17.8 million as of March from 18.1 million people as compared to last year in December. The Report states that the unemployment rate in Kenya stands at 13.7 per cent as of March this year while it stood 12.4 per cent in December 2019.

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Mama T (not her real name) is among millions of Kenyans who have been affected by containment measures put in place to curb the spread of the virus, either by losing their source of income or having to work under tough guidelines put in place by the MOH.

As young mother and an event organizer, she has found it hard to explain to her children why they cannot go to school or socialize freely with their peers as before.

“Sometimes it gets difficult as they do not understand what is happening due to their age, this at times becomes hard on me as they often think I am punishing them,”

Her contract was put on hold as no event or public gatherings can take place due to the pandemic. This has brought other challenges along with it, as she has to find means of fending for her family expenditures that including rent and food.

“I often wake up in the middle of the night with worries about my next move as the pandemic does not exhibit any signs of easing up,” she says. She adds that she has been forced to sort for manual jobs to keep her family afloat.

Ms. Mary Wahome, a Counseling Psychologist and Programs Director at ‘The Reason to Hope,’ in Karen, Nairobi says that such kind of drastic life changes have an adverse effect on one’s mental status including their family members and if not addressed early can lead to depression among other issues.

“We have had cases of people indulging in substance abuse to deal with the uncertainty and stress brought about by the pandemic, this in turn leads to dependence and also domestic abuse,”

Sam Njoroge , a waiter at a local hotel in Kiambu, has found himself indulging in substance abuse due to challenges he is facing after the hotel he was working in was closed down as it has not yet met the standards required by the MOH to open.

“My day starts at 6am where I go to a local pub, here I can get a drink for as little as Sh30, It makes me suppress the frustration I feel.” he says.

Sam is among the many who have found themselves in the same predicament and resulted to substance abuse finding ways to beat strict measures put in place by the government on the sale of alcohol so as to cope.

Mary says, situations like Sam’s are dangerous and if not addressed early can lead to serious complications, including addiction and dependency, violent behavior and also early death due to health complications.

She has, however, lauded the government for encouraging mental wellness and also launching the Psychological First Aid (PFA) guide in the wake of the virus putting emphasis on the three action principal of look, listen and link. “When we follow this it will be easy to identify an individual in distress and also offer assistance”.

Mary has urged anyone feeling the weight of the virus taking a toll on them not to hesitate but look for someone to talk to.

“You should not only seek help from a specialist but also talk to a friend, let them know what you are undergoing and how you feel, this will help ease their emotional stress and also find ways of dealing with the situation they are facing,” She added

Mary continued to stress on the need to perform frequent body exercises as a form of stress relief, reading and also taking advantage of this unfortunate COVID-19 period to engage in hobbies and talent development.

“Let people take this as an opportunity to kip fit, get in touch with one’s inner self and  also engage in   reading that would  help expand their knowledge.

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