Use of cannabis by men of child-bearing age significantly alters their sperm and affects fertility, a new study has shown, re-igniting the age-old debate of the effects of the plant.
The study conducted by Duke University Medical Centre revealed that use of bhang by men causes potential risk to their future children as the active ingredient of the drug, tetrahydrocannabinol (THC), causes sperm to change.
“What we have found is that the effects of cannabis use on males and their reproductive health are not completely null, in that there’s something about cannabis use that affects the genetic profile in sperm,” said Dr Scott Kollins, professor in psychiatry and behavioral sciences at Duke University and senior author of the study funded by the John Templeton Foundation.
The research paper, “Cannabinoid exposure and altered DNA methylation in rat and human sperm,” published on December 19, studied the effects of THC in both humans and male rats with a view to find out the effect of the drug before conception took place.
CHANGES IN DNA
It was discovered that the chemical affects epigenetics, triggering structural and regulatory changes in the DNA of users’ sperm.
According to WhatisEpigenetics.com, “epigenetics is the study of heritable changes in gene expression (active versus inactive genes) that do not involve changes to the underlying DNA sequence, a change in phenotype without a change in genotype, which in turn affects how cells read the genes.”
Epigenetic change is a natural occurrence that can also be influenced by several factors including age, the environment or lifestyle, in this case, the use of marijuana (bhang), and disease state such as cancer.
“We don’t yet know what that means, but the fact that more and more young males of child-bearing age have legal access to cannabis (in the US) is something we should be thinking about,” Dr Kollins said.
Experiments in rats and a study with 24 men found that THC appears to target genes in two major cellular pathways and alters DNA methylation, a process essential to normal development.
DNA methylation is an epigenetic mechanism that occurs by the addition of a methyl (CH3) group to DNA, thereby often modifying the function of the genes and affecting gene expression.
According to lead author Susan Murphy, an associate professor and chief of the Division of Reproductive Sciences in obstetrics and gynecology at Duke University, one of the pathways affected by use of the drug is involved in helping bodily organs reach their full size while the other pathway involves a large number of genes that regulate growth during development.
“In terms of what it means for the developing child, we just don’t know. It is unknown whether sperm affected by THC could be healthy enough to even fertilize an egg and continue its development into an embryo,”Dr Murphy said.
The study also revealed that in humans, cannabis use was also associated with significantly lower sperm concentration. She suggests that men who would like to conceive should stop using the drug at least six months before trying for a baby, in case the effects can somehow be passed on to the next generation.
The study shows that about 150 million people worldwide use the drug and its use may continue to grow as it becomes more accepted. Medical use of marijuana is legal in 33 American states.
The potential effects of bhang use are very close home since in September Kibra MP Ken Okoth wrote to Speaker Justin Muturi asking for facilitation in preparing the Marijuana Control Bill.
Singer speaks after attacking lover at WCB signee Zuchu’s star-studded concert
56 minutes ago
On 18 July, there was fanfare at the Mlimani City Hall in Dar es Salaam as WCB signee Zuchu held a thanksgiving concert months after her debut EP, I Am Zuchu. The event dubbed ‘Ahsante Nashukuru’ mainly featured performances by artistes from the WCB stable and attracted the whos-who in the Tanzanian entertainment and political scenes.
However, singer Gigy Money who also performed made the headlines for the wrong reasons after getting into a scuffle with her lover during the much-publicised concert.
READ ALSO: I was bewitched by a friend – Gigy Money
Peaceful arrival, later chaos
Moments earlier, Gigy and her Nigerian man were seen arriving arm in arm at the event whose highlight featured Zuchu receiving a brand new car from WCB head honcho Diamond Platnumz. Donning matching outfits, the couple was spotted on the red carpet as the paparazzi scrambled to capture the moment. However, all hell breaks loose later and viral videos depict the visibly angered Nigerian arguing with a bouncer at the entrance. After a tense confrontation, Gigy’s man is seen being led by the screaming bouncer towards the exit. Shortly after, a similarly irritated Gigy emerges and follows the pair.
“Gigy! Wewe Gigy wewe!” a woman in the background is heard dissuading the singer from pursuing them but the singer pays no heed and heads for the pair.
“You want to beat me?” the boyfriend is heard asking an approaching Gigy as the bouncer acts as a barrier between them. The bouncer manages to steer the incensed man towards the exit as Gigy follows behind, hurling obscenities.
At some point, a barefoot Gigy turns into a sprint before throwing one of her shoes which hits the man who then responds with an insult. Another bouncer finally intervenes and the two are separated. Gigy then asks for her vehicle so she can head home before warning the press against sharing videos of the incident.
Though the cause of their tiff is still unknown Gigy later made reference to the shocking incident in a social media post, hinting that alcohol had a part to play in the fracas. In another post, Gigy shared a photo alongside her estranged lover writing: “My mad man looked handsome before his demons arose and mine arose too.”
‘Running over Ali Kiba’
Gigy is not new controversy and recently said she’d run over her ex, singer Ali Kiba for breaking her heart.
“I will knock all of them down, I mean I will kill them. In fact, I will flatten them like chapatis. The first person I will knock down and kill is Ali Kiba. Actually, I don’t need a weak car, I need a Fuso so that when I knock him down I will be sure he doesn’t survive,” Gigy told Ayo TV.
Dating Kiba brothers
Gigy had in the past admitted to dating both Ali Kiba and his younger brother, Abdu Kiba. She solely laid the blame on Chekecha singer for pursuing her despite knowing that she’d been with his younger brother. Abdu expressed being heartbroken after learning the two had a fling, prompting him to marry.
“I was very hurt on hearing that Ali was dating Gigy Money because I dated her first before she became famous. But it’s alleged that Ali didn’t know. It hurt me for a while till when I married,” said Abdu.
Defunct Nairobi County Council Nurses Go On Strike, Citing Discrimination By The Government
Why Jahmby Kokai is happy her TV anchor dream never came true
37 minutes ago
Popular media personality Jahmby Koikai narrated how her first attempt at auditioning as a TV host backfired and she was sent home on the first day of the audition. Reliving her prime days, Jahmby narrated how she was determined to follow her dream of becoming a news anchor after completing her degree.
“There was a reality show that was running on one major TV channel here in Kenya, searching for the next top news anchor. I’ve always had the knack for news. At the time, I was working at Metro FM. Walked to my boss and asked him if he was ok with me participating in this competition. He agreed to it.
“Auditions were at Film Studios. The queue stretched all the way to the showground. I was at the back kabisa. Imagine 300 people before you. Then we got the briefing paper and it indicated, ‘no persons with experience in a media house allowed to participate in this audition’. Mimi Jahmby Koikai, nirudi home after watu 300 kukuwa mbele yangu?” she posed.
According to the endometriosis survivor, she went ahead to audition for the position despite the warning and was the first contestant to be sent packing.
“So I stayed in line until I got to the audition room. The judges were a few people I was in campus with. I felt a wave of despair. Like I’m here auditioning, yet my classmates will be judging me? I did my thing and I was considered. We got into the house and we were assigned to different groups. I was the group leader and we won the challenge. Later that evening, we were driven back to Film Studios for a briefing. The presenter of the show said some of us have to go home.
“My name was called out first amongst other great people. We were dropped home. I cried. It felt like I’d lost such a great opportunity. My mom and late grandma were so sad cos they loved to watch me do the news,” she narrated.
Later, Jahmby auditioned for another TV opportunity only to miss out as well.
“Then came another opportunity over 10 years ago, I saw a TV ad and decided to apply for the news anchor position. I didn’t get the job.”
However, due to endometriosis, Jahmby was forced to put her dreams on hold and concentrate on getting better. According to her, it is as though God had better plans for her and is grateful to not have gotten the jobs.
“I battled severe endometriosis in silence for over 19 years. I think of how engaging the newsroom is and I’m grateful I wasn’t in that space. I’d have utilized all my sick-leaves and off-days and just declared redundant.”
There was a reality show that was running on one major TV channel here in Kenya, searching for the next top news anchor. I’ve always had the knack for news. At the time, I was working at Metro Fm. Walked to my boss and asked him if he was ok with me participating in this competition. He agreed to it. Auditions were at Film Studios. The queue stretched all the way to the showground. I was at the back kabisa. Imagine 300 people before you. Then we got the briefing paper and it indicated, ‘no persons with experience in a media house allowed to participate in this audition’. Mimi Jahmby Koikai, nirudi home after watu 300 kukuwa mbele yangu? Nikasema zi. So I stayed in line until I got to the audition room. The judges were a few people I was in campus with. I felt a wave of despair. Like I’m here auditioning, yet my classmates will be judging me? I did my thing and I was considered. We got into the house and we were assigned to different groups. I was the group leader and we won the challenge. Later that evening, we were driven back to Film Studios for a briefing. The presenter of the show said, some of us have to go home. My name was called out first amongst other great people. We were dropped home. I cried. It felt like I’d lost such a great opportunity. My mom and late grandma were so sad cos they loved to watch me do the news. Then came another opportunity over 10years ago, I saw a TV ad and decided to apply for the news anchor position. As you see in this pic, I got my hair done at Ralph’s Hair Salon, new suit etc. I didn’t get the job. After KBC, I never got to anchor the news again. I’m grateful I did not get the job even though I felt dejected at the time. I battled severe Endometriosis in silence for over 19years. I think of how engaging the newsroom is and I’m grateful I wasn’t in that space. I’d have utilised all my sick-leaves and off-days and just declared redundant. There are many people like me who are bound by chronic illness and cannot do the things they love. I share your pain. But there’s hope. I’m grateful to God for His reminder that He will restore to you all the years that the locusts have eaten. Also Jer 29:11